Cell Signaling Technology

Cell Signaling Technology公司自主开发的新位点抗体

Cell Signaling Technology (CST)公司现在提供许多针对新发现的蛋白修饰位点(磷酸化,乙酰化等)的抗体。这些位点都是被CST的科学家利用PTMScan®技术首先发现的,PTMScan®是CST用来研究翻译后修饰位点的专用的质谱平台。PTMScan®利用基序抗体进行细胞裂解物的肽免疫亲和纯化,同时联合LC串联质谱来鉴定和对修饰状态水平的变化进行定量。采用的基序抗体对磷酸化(酪氨酸,丝氨酸,苏氨酸)肽、乙酰化肽或泛素化标签肽是特异的,可以用来分析细胞磷酸化、乙酰化或泛素化的状态。

关于这方面的更多信息和CST其他新发现的修饰位点,包括其他更多的发表资料,您可以在PhosphoSitePlus®www.phosphosite.org找到,这是CST开发和维护的修饰位点数据库。

Phospho-53BP1 (Thr543) Antibody #3428

Also reported in PMID(s): 17525332

Phospho-c-Abl (Tyr89) (61A6) Rabbit mAb #3098

Also reported in PMID(s): 1691203618775435

Phospho-ALK (Tyr1078) Antibody #4144

Also reported in PMID(s): 19887368

Phospho-ALK (Tyr1278) (D59G10) Rabbit mAb #6941

Also reported in PMID(s): 1593864419887368204241602039318521045017

Phospho-ALK (Tyr1278/1282/1283) Antibody #3983

Also reported in PMID(s): 1988736817998938

Phospho-ALK (Tyr1278) Antibody #3710

Also reported in PMID(s): 1593864419887368204241602039318521045017

Phospho-ALK (Tyr1282/1283) Antibody #3714

Also reported in PMID(s): 1988736817998938

Phospho-ALK (Tyr1586) (3B4) Rabbit mAb #3348

Phospho-ALK (Tyr1586) Antibody #3343

Phospho-Axl (Tyr702) (D12B2) Rabbit mAb #5724

Also reported in PMID(s): 1701652017646646185639271851586019534553

Phospho-CaMKII (Tyr231) Antibody #3356

  • Applications: W
  • Reactivity: R, (H)
  • Pathway: Neuroscience

Also reported in PMID(s): 18034455

Phospho-Catenin δ-1 (Tyr904) Antibody #2910

Also reported in PMID(s): 1856392718707149185158601884650720007894

Phospho-Desmoplakin (Ser165/166) Antibody #5885

  • Applications: W
  • Reactivity: H, M, R, Mk
  • Pathway: Adhesion
  • CST Publication: 20736484

Also reported in PMID(s): 1927636821183079

Phospho-DR6 (Ser562) Antibody #7616

Phospho-DRP1 (Ser616) Antibody #3455

Also reported in PMID(s): 173010551749475218187866180880871823485618669648,18847512188386871884650719664995

Phospho-EGF Receptor (Tyr998) (C24A5) Rabbit mAb #2641

Also reported in PMID(s): 156570671595156917016520173893951764664617870612,1827152618669648187760481851586019531499

Phospho-EphA2 (Tyr594) Antibody #3970

Also reported in PMID(s): 159515691701652017192257183879451856392718578522,186919761877604818707149185158601884650719193766193691951953455320007894

Phospho-EphA2 (Tyr772) Antibody #8244

Also reported in PMID(s): 159515691701652017192257173893951764664617870612,183879451856392718578522186919761877604818707149185158601884650719369195,195345531965810019366988200078942056209621049007

Phospho-FLT3 (Tyr969) (C24D9) Rabbit mAb #3463

Also reported in PMID(s): 166277591943850519369195

Phospho-FoxO3a (Ser294) Antibody #5538

Also reported in PMID(s): 18204439

Phospho-HER3/ErbB3 (Tyr1328) Antibody #8017

Also reported in PMID(s): 170165201738939519534553

Phospho-Mre11 (Ser676) Antibody #4859

Also reported in PMID(s): 19709933

Phospho-MYPT1 (Ser507) Antibody #3040

Also reported in PMID(s): 18088087186696481884650719367708

Phospho-MYPT1 (Ser668) Antibody #3048

Also reported in PMID(s): 19367708

Phospho-NMDAR2A (Tyr1246) Antibody #4206

  • Applications: W, IP
  • Reactivity: R, (H, M)
  • Pathway: Neuroscience

Also reported in PMID(s): 19834457

Phospho-NMDAR2B (Tyr1070) Antibody #4209

  • Applications: W
  • Reactivity: R, (H, M)
  • Pathway: Neuroscience

Also reported in PMID(s): 18034455

Phospho-NMDAR2B (Ser1284) Antibody #5355

Phospho-NuMA (Ser395) Antibody #3429

Also reported in PMID(s): 17525332

Phospho-PDGF Receptor α (Tyr849)/PDGF Receptor β (Tyr857) (C43E9) Rabbit mAb #3170

Also reported in PMID(s): 18515860

Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) Antibody #4228

Also reported in PMID(s): 15951569164930401701652017164333 1738939517646646,180344551832210518515860185639271858739819010331190731471992018420007894

Phospho-PKM2 (Tyr105) Antibody #3827

Also reported in PMID(s): 16464493176466461803445518563927

Phospho-PNK1 (Ser114/Thr118) Antibody #3522

Also reported in PMID(s): 17525332186696481966499419664995

Phospho-PPIG (Ser376) Antibody #3804

Phospho-PSD93 (Tyr340) Antibody #2930

  • Applications: W, IP
  • Reactivity: R
  • Pathway: Neuroscience

Also reported in PMID(s): 18034455

Phospho-PSD95 (Tyr236/Tyr240) Antibody #3919

  • Applications: W
  • Reactivity: R, (H, M)
  • Pathway: Neuroscience

Also reported in PMID(s): 18034455

Phospho-REPS1 (Ser709) Antibody #6884

Also reported in PMID(s): 183180081870714918846507193677081914431919366988,198541401969033220166139204154952016405921183079

Phospho-RIP2 (Ser176) Antibody #4364

Also reported in PMID(s): 16824733175253321869197619369195

Phospho-RSK2 (Tyr529) Antibody #9324

Also reported in PMID(s): 1778520218156174

Phospho-SATB1 (Ser47) Antibody #4028

Phospho-Semaphorin 4B (Ser825) Antibody #5622

Also reported in PMID(s): 186696481884650719854140

Phospho-SHIP2 (Tyr986/987) Antibody #2008

Also reported in PMID(s): 17219406185158601953455320007894

Phospho-TIF1β (Ser824) Antibody #4127

Also reported in PMID(s): 168621431696424317525332179423931840632718657500,186696481904746020026654

Phospho-TNK1 (Tyr277) Antibody #4553

Also reported in PMID(s): 18691976

应用:W=免疫印迹  IP=免疫沉淀  IHC-P=免疫组化(石蜡)  IHC-F=免疫组化(冰冻)  IF-IC=免疫荧光(免疫细胞化学) F=流式细胞术

反应性:H=人  M=小鼠  R=大鼠Hm=仓鼠 Mk=猴 Hr=马

括号中的种属基于序列100%的同源性,预测可以反应。

Products

Applications