Product Pathways - Neuroscience
Phospho-Synapsin-1 (Ser605) (D4B9I) Rabbit mAb #88246
|88246S||100 µl ( 10 western blots )||￥3,900.00 现货查询||购买询价|
|88246||carrier free & custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting,
Specificity / Sensitivity
Phospho-Synapsin-1 (Ser605) (D4B9I) Rabbit mAb recognizes endogenous levels of Synapsin-1 protein only when phosphorylated at Ser605 (corresponds to Ser603 in rat).
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser605 of human Synapsin-1 protein.
Western blot analysis of extracts from mouse brain, mouse lung, and rat brain using Phospho-Synapsin-1 (Ser605) (D4B9I) Rabbit mAb (upper) and and β-Actin (D6A8) Rabbit mAb #8457 (lower).
Synapsins, a group of at least five related members (synapsins Ia, Ib, IIa, IIb, and IIIa), are abundant brain proteins essential for regulating neurotransmitter release (1,2). All synapsins contain a short amino-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I (1). Phosphorylation of the synapsin amino-terminal domain at Ser9 inhibits its binding to phospholipids and dissociates synapsins from synaptic vesicles (2).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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