Product Pathways - Metabolism
IP6K3 (D9O7J) Rabbit mAb #54322
|54322S||100 µl ( 10 western blots )||￥3,250.00 现货查询||购买询价|
|54322||carrier free & custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation,
Specificity / Sensitivity
IP6K3 (D9O7J) Rabbit mAb recognizes endogenous levels of total IP6K3 protein. This antibody does not cross-react with IP6K1 or IP6K2 proteins.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala140 of human IP6K3 protein.
Western blot analysis of extracts from various cell lines using IP6K3 (D9O7J) Rabbit mAb.
Inositol hexakisphosphate kinase 3 (IP6K3) is a member of the inositol hexakisphosphate kinase family (1). These kinases are essential for producing inositol pyrophosphates (1). IP6K3 is highly expressed in the cerebellar Purkinje cells, interacts with adducin and spectrin, and plays an important role in determining the cytoskeletal organization and function of these cells (1). In addition, the expression of IP6K3 increases upon treatment with titanium dioxide nanoparticles suggesting a role for IP6K3 in the genotoxicity caused by these nanoparticles (2).
- Fu, C. et al. (2015) J Neurosci 35, 11056-67.
- El-Said, K.S. et al. (2014) J Nanobiotechnology 12, 48.
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For Research Use Only. Not For Use In Diagnostic Procedures.
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