Cell Signaling Technology

Product Pathways - Neuroscience

Musashi Antibody #2154

MSI   MSI1H   RNA-binding protein Musashi homolog 1   sc-98845  

No. Size Price
2154S 100 µl ( 10 western blots ) ¥3,250.00 现货查询 购买询价 防伪查询
2154 carrier free & custom formulation / quantityemail request
Applications Dilution Species-Reactivity Sensitivity MW (kDa) Isotype
W 1:1000 Human,Mouse,Rat, Endogenous 35 Rabbit

Species cross-reactivity is determined by western blot.

Applications Key: W=Western Blotting,


Species predicted to react based on 100% sequence homology: Zebrafish,

Specificity / Sensitivity

Musashi Antibody detects endogenous levels of total Musashi 1 and 2 protein.

Musashi Antibody 兔单抗识别内源性的总Musashi 1和Musashi 2蛋白。

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues of human Musashi. Antibodies are purified by protein A and peptide affinity chromatography.


Western Blotting

Western Blotting

Western blot analysis of extracts from IEC-6 and LS174T cells, using Musashi Antibody.

Western blot分析IEC-6和LS174T细胞提取物,使用的抗体是Musashi Antibody 兔多抗。



Confocal immunofluorescence images of the subventricular zone of rat striatal sections labeled with Musashi Antibody (red) and Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb (Alexa Fluor® 488 Conjugate) #4854 (green). Proliferating/mitotic cells are labeled with Phospho-Histone H3 (Ser10) (6G3) Mouse mAb #9706 (blue).

共聚焦免疫荧光分析大鼠脑室下纹状体区域,使用Musashi Antibody 兔多抗(红色)和Phospho-S6 Ribosomal Protein (Ser235/236) (2F9) Rabbit mAb (Alexa Fluor® 488 Conjugate) #4854(绿色)进行标记。增生/分裂细胞用 Phospho-Histone H3 (Ser10) (6G3) Mouse mAb 兔单抗#9706(蓝色)标记。


Musashi-1 and Musashi-2 are RNA-binding proteins which play a role in asymmetric cell division of ectodermal precursor cells by regulating the translation of target mRNA. Both family members augment Notch signaling and repress the translation of m-Numb, a protein that positively modulates differentiation of neural stem cells into neurons. Thus, Musashi contributes to the maintenance of neural stem cells (1). While Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells (2-4).


  1. Okano, H. et al. (2005) Exp. Cell Res. 306, 349-56.
  2. Sakakibara, S. et al. (1996) Dev. Biol. 176, 230-42.
  3. Potten, C.S. et al. (2003) Differentiation 71, 28-41.
  4. Clarke, R.B. et al. (2005) Dev. Biol. 277, 443-56.

Application References

Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know!


Companion Products

For Research Use Only. Not For Use In Diagnostic Procedures.

Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.

Alexa Fluor is a registered trademark of Life Technologies Corporation.

Cell Signaling Technology® is a trademark of Cell Signaling Technology, Inc.

用户评论 --- 共 0


我要参与评论 :