Product Pathways - Cytoskeletal Signaling
β-Tubulin (D2N5G) Rabbit mAb #15115
|15115S||100 µl ( 10 western blots )||￥3,100.00 现货查询||购买询价|
|15115||carrier free & custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IHC-P=Immunohistochemistry (Paraffin), IF-IC=Immunofluorescence (Immunocytochemistry),
Specificity / Sensitivity
β-Tubulin (D2N5G) Rabbit mAb recognizes endogenous levels of total β-tubulin protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human β-tubulin protein.
Confocal immunofluorescent analysis of NIH/3T3 cells using β-Tubulin (D2N5G) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using β-Tubulin (D2N5G) Rabbit mAb.
Western blot analysis of extracts from HeLa, NIH/3T3, and KNRK cells using β-Tubulin (D2N5G) Rabbit mAb.
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins (1).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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