Product Pathways - Cytoskeletal Signaling
α-Smooth Muscle Actin Antibody #14968
|14968S||100 µl ( 10 western blots )||￥3,250.00 现货查询||购买询价|
|14968||carrier free & custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting,
Specificity / Sensitivity
α-Smooth Muscle Actin Antibody recognizes endogenous levels of total α-smooth muscle actin protein.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human α-smooth muscle actin protein. Antibodies are purified by protein A and peptide affinity chromatography.
Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility (1). The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells (1).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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