Cell Signaling Technology

Product Pathways - Metabolism

FABP3 (A7) Mouse mAb #14780


No. Size Price
14780S 100 µl ( 10 western blots ) ¥3,250.00 现货查询 购买询价
14780 carrier free & custom formulation / quantityemail request
Applications Dilution Species-Reactivity Sensitivity MW (kDa) Isotype
W 1:1000 Human, Endogenous 14 Mouse IgG1
IP 1:100

Species cross-reactivity is determined by western blot.

Applications Key: W=Western Blotting, IP=Immunoprecipitation,

Specificity / Sensitivity

FABP3 (A7) Mouse mAb recognizes endogenous levels of total FABP3 protein.

Source / Purification

Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human FABP3 protein.

Western Blotting

Western Blotting

Western blot analysis of extracts from human heart tissue and human skeletal muscle using FABP3 (A7) Mouse mAb.


Fatty acid binding proteins (FABPs) are cytoplasmic lipid chaperones that bind fatty acids and lipids for transport to various cellular components (1,2). Research studies demonstrate differential FABP expression in several types of tumors and their normal-cell counterparts (3). Fatty acid binding protein 3 (FABP3) is predominantly expressed in heart, skeletal muscle, brain, and mammary gland (4). FABP3 may play a role in supplying energy to the heart and other tissues (5). The release of FABP3 from the heart upon infarction is used as a serum marker for myocardial stress and cardiotoxicity (6). Additional studies suggest that FABP3 is a potential tumor suppressor in breast cancer (7).

  1. Storch, J. and Thumser, A.E. (2010) J Biol Chem 285, 32679-83.
  2. Haunerland, N.H. and Spener, F. (2004) Prog Lipid Res 43, 328-49.
  3. Khan, S.H. and Sorof, S. (1994) Proc Natl Acad Sci U S A 91, 848-52.
  4. Heuckeroth, R.O. et al. (1987) J Biol Chem 262, 9709-17.
  5. Binas, B. et al. (1999) FASEB J 13, 805-12.
  6. Lippi, G. et al. (2013) Clin Biochem 46, 26-30.
  7. Nevo, J. et al. (2010) Oncogene 29, 6452-63.

Application References

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Companion Products

For Research Use Only. Not For Use In Diagnostic Procedures.

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