Product Pathways - Metabolism
ANT2/SLC25A5 (E2B9D) Rabbit mAb #14671
2F1 AAC2 Adenine nucleotide translocator 2 adenine nucleotide translocator 2 (fibroblast) adenine nucleotide translocator). member 5 ADP.ATP carrier protein 2 ADP.ATP carrier protein. fibroblast isoform ADP/ATP carrier protein ADP/ATP translocase 2 ADT2 ANT 2 ANT2 SLC25A5 solute carrier family 25 (mitochondrial carrier Solute carrier family 25 member 5 T2 T3
|14671S||100 µl ( 10 western blots )||￥3,100.00 现货查询||购买询价|
|14671||carrier free & custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation,
Specificity / Sensitivity
ANT2/SLC25A5 (E2B9D) Rabbit mAb recognizes endogenous levels of total ANT2/SLC25A5 protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly156 of human ANT2/SLC25A5 protein.
Western blot analysis of extracts from various cell lines using ANT2/SLC25A5 (E2B9D) Rabbit mAb.
Adenine nucleotide translocase 2 (ANT2/SLC25A5) is a member of the adenine nucleotide translocase family of mitochondrial inner membrane proteins that function differently in metabolic and apoptotic pathways (1). Research studies indicate that ANT2 expression in undifferentiated, proliferating cells correlates with the rate of glycolytic metabolism and may be an indicator of carcinogenesis (2). Suppression of ANT2/SLC25A5 expression by specific RNA interference in human breast cancer cells promotes apoptosis and inhibits tumor cell growth (2), which suggests a cytoprotective role of ANT2/SLC25A5 (1,3).
- Brenner, C. et al. (2011) Oncogene 30, 883-95.
- Chevrollier, A. et al. (2011) Biochim Biophys Acta 1807, 562-7.
- Jang, J.Y. et al. (2008) Breast Cancer Res 10, R11.
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